| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95e7278486e9ba6a3c0365c6c302909f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-805 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-805
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2001-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f16fda505e673aee5a51f667eb13d1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ec237c6ca866dfee117b8f506853a18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b89ce1b4d86de881046cf419592397ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39229bb594f0fffdd74467024ac0701e |
| publicationDate |
2004-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6812328-B2 |
| titleOfInvention |
Low oxygen affinity mutant hemoglobins |
| abstract |
Non-naturally occurring mutant hemoglobins rHb (betaN108Q) and rHb (betaL105W) are provided that have a lower oxygen affinity than that of native hemoglobin, but high cooperativity in oxygen binding. rHb (betaN108Q) also exhibits enhanced stability against autoxidation. The mutant hemoglobins are preferably produced by recombinant DNA techniques. Such mutant hemoglobins may be used as a component of a blood substitute and hemoglobin therapeutics. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015100235-A1 |
| priorityDate |
2000-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |