| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate |
2001-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81772df2a7159fa4a3e75a703e82c9d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2364e2279d8b857340790da0f7f1faa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17b48d8db601723e832cd8f90339073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b995ba5f6950dd69c88e0d4673b368 |
| publicationDate |
2004-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6808923-B2 |
| titleOfInvention |
Episomally replicating lentiviral vectors |
| abstract |
The invention is directed to a lentiviral vector system that can be used for episomal replication of a desired gene. The vector system contains a first vector containing a lentiviral gag gene encoding a lentiviral gag protein, a second vector containing an env gene encoding a functional envelope protein, and a lentiviral pol gene encoding a lentiviral pol protein. The pol protein is at least integrase, but that the integrase has been modified so that it is not capable of integration. This pol gene can be on the first or second vectors or on a third vector. The lentiviral gag and pol and the envelope protein are not on a single vector, and these vectors do not contain nucleotides to effectively package lentiviral RNA. The system also contains another vector having a nucleic acid sequence encoding a target molecule operably linked to a component of an episomal replicon and a lentiviral packaging sequence. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018232079-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729741-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2848937-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2386564-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009111738-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018071709-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003044981-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7262049-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3187585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2586461-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009191155-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009053295-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8691944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012170765-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010292161-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3072901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3069730-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2873423-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2568289-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2679596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8759300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7786091-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011166209-A1 |
| priorityDate |
1999-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |