| abstract |
A polymer comprising the unit (I) wherein R is selected form the group consisting of hydrogen, C1-C18 alkyl, C1-C18 aralkyl, C1-C18 alkaryl, carboxylic acid, carboxy-C1-6alkyl, or any one of the C1-C18 alkyl, C1-C18 alkenyl, C1-C18 aralkyl, C1-C18 alkaryl substituted with a heteroatom within, or attached to, the carbon backbone; R<1 >is selected from the group consisting of hydrogen, C1-C6 alkyl groups; X is an acylating agent and wherein the polymer has a polydispersity of less than 1.4, preferably less than 1.2 and a molecular weight (Mw) of less than 100,000, the polymer is preferably made by controlled radical polymerization and is useful in the production of polymer drug conjugates with desirable biological profiles. |