| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_277d0d4e9b9bf1a7af176e3162d8085e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1999-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4134fc9e44f1e1fc1ab0a42b6a8332b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf18ec77325e37fc2b73cca12b393ecb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_135671c09ae7d3d98281985f77eb0f56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7c65b1068162f12e1d8e98ec5dc8ffc |
| publicationDate |
2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6797807-B1 |
| titleOfInvention |
Compounds and methods for cancer therapy |
| abstract |
Methods for using modulating agents to enhance or inhibit occludin-mediated cell adhesion in a variety of in vivo and in vitro contexts are provided. Within certain embodiments, the modulating agents may be used for cancer therapy or to increase immune cell infiltration into tumors. The modulating agents comprise at least one occludin cell adhesion recognition sequence or an antibody or fragment thereof that specifically binds the occludin cell adhesion recognition sequence. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by the other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7601514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8058244-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008286861-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005159346-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010204088-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7709443-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8492345-B2 |
| priorityDate |
1997-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |