| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33dafb5bbc2ec47ebcb7becbbe60f704 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-64 |
| filingDate |
2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_922f528ffed35980509809600eefd3b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac1256657a5f49b5bb274682ec0efb01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8b56c5429de80d81d249a57a78dd05 |
| publicationDate |
2004-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6790964-B1 |
| titleOfInvention |
Process for the preparation of 7-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid esters |
| abstract |
The present invention provides a method of producing 7-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester (VII) economically, industrially advantageously and efficiently in a large amount. The present invention relates to a production method of compound (VII), which includes reacting epoxide (I) with amine (II) to give aminodiol (III), reacting the aminodiol (III) with a sulfonylating agent in the presence of a base to give azabicyclohept-2-ene (IV), reacting the azabicyclohept-2-ene (IV) with alcohol (V) in the presence of a Lewis acid to give azabicyclohept-3-ene (VI), and eliminating the 7-position substituent R<2 >from the azabicyclohept-3-ene (VI) |
| priorityDate |
1999-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |