| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b2ad2fce14121a6e9d223fd1bd9a622 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 |
| filingDate |
2002-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee61a4db55416d2d58f2220d4bdd8fcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dd71bca5de0856b171265aa7ae01c95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5940bc57c5b550ef3b3b40a824640e9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5bd71dacc9aa7c901449901269c1084 |
| publicationDate |
2004-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6787142-B2 |
| titleOfInvention |
Mutant human hepatitis B viral strain and uses thereof |
| abstract |
This invention provides an isolated strain of Hepatitis B virus designated Human Hepatitis B Virus Surface Antigen-'S'-133 Oon Strain (Methionine to Threonine) which constituent viral genome is deposited under Accession Nos. P97121501, P97121502 and P97121503 with the European Collection of Cell Culture on 15<th >December 1997. This invention also provides an isolated nucleic acid encoding a polypeptide which is a mutant major surface antigen of a strain of hepatitis B virus, such polypeptide having an amino acid sequence which differs from the amino acid sequence of a major surface antigen of a wild type hepatitis B virus in that the amino acid at position number 133 of such polypeptide is a threonine rather than a methionine. This invention also provides an isolated nucleic acid which encodes a peptide, wherein the peptide is encoded by a nucleic acid molecule comprising nucleotides 527 through 595 of SEQ. I.D. No. 1 and the purified peptide. This invention also provides various methods of using the disclosed isolated nucleic acid and peptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009221018-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497808-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006052414-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730808-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008263250-A1 |
| priorityDate |
2001-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |