| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9fbfeba067df93dd1d2b4417267540f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4da9f2a43503b4b6190d5987142c6e11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e231cceedbb8142dc2ba2c8d6764802e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41a83a3a7bffc3763ca2c2d8d28f6bad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_289f72060be1b2d6a98fb945fe3da909
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93fdca3454ec6cd8cb976c3e10f4055b |
| publicationDate |
2004-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6777431-B2 |
| titleOfInvention |
Non-convalent thrombin inhibitors |
| abstract |
The present invention provides compounds which have a pyrazinone or pyridinone ring at P3 and an optionally substituted heteroaryl group at P1. These compounds have biological activity as active and potent inhibitors of thrombin. Their pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds and pharmaceutical compositions comprising these compounds as therapeutic agents for treatment of disease states in mammals which are characterized by abnormal thrombosis are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11188604-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9268862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9965561-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014229459-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10599735-B2 |
| priorityDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |