Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a135a933620c99beab01d4ac785d25 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-85 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
1999-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2004-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a9be28c049e3f96fd4e384c26355bae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dfce06cd19e353345ab1e856625829f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d6c8fa4a9e9cfb49ddc411c536a5952 |
publicationDate |
2004-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6777235-B1 |
titleOfInvention |
Complementation trap |
abstract |
Methods and DNA constructs are provided for detection and manipulation of a target eukaryotic gene whose expression is restricted to certain tissues or specialized cell types. The methods include transforming a cell with a first indicator component under the control of a promoter selected for its restricted expression in a particular cell or tissue. The cell is also transformed with a gene trap vector encoding a second indicator component. The cell is allowed to differentiate to produce specialized cell or tissue which is monitored for expression of both the first and second indicator components, thereby detecting a gene into which the trap vector has integrated which is expressed in the same cell or tissue type as the selected promoter. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7179595-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7312075-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004265901-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011117642-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007243541-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8722408-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005208466-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009202988-A1 |
priorityDate |
1997-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |