abstract |
The present invention relates to certain spirooxindole derivatives and to pharmaceutically acceptable salts thereof, which exhibit good analgesic properties and are effective in the treatment of chronic pain. The derivatives have the structure of formula I:wherein:Ar is benzene or pyridine;X is NHCO-; -CONH-; or -NH-SO2-;Y is a single bond; andZ is -CH=CHCH2. |