Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fdaffe64e0056ceff97698a913ed913 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10343 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
filingDate |
2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2004-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_723dca01629561652fe95bd9e4577a03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8e7f945203c29f1765a3a065912c00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7199ca55b381d67a806e5b8a8c1f25f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b0edb8f3256d6fbdd203abe42454e7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0112945aa7b7eeb0376cb4e4583fb47a |
publicationDate |
2004-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6759231-B2 |
titleOfInvention |
Phage with nuclear localization signal |
abstract |
A lambda phage with a nuclear localization signal has been obtained by constructing a vector capable of expressing a fused protein between a gpD protein constituting the head of a lambda phage and a nuclear localization signal sequence, transforming Escherichia coli with this vector, and propagating a mutant lambda phage which cannot express the gpD protein in E. coli in this transformant. It has been confirmed that the resulting lambda phage is capable of packaging lambda phage DNAs of 80% and 100% genome sizes. After further confirming that the nuclear localization signal exposed on the outside of the head of this phage, this phage has been microinjected into cells to analyze its nuclear localization activity. Thus, it has been clarified that this phage has a nuclear localization activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008305119-A1 |
priorityDate |
1996-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |