Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d20cc305706685e26da965e2bb22167f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2828 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2004-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a66442235d53f4a808e79801854de487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8c4ef1fbd69bd6ef39250dc091b11d1 |
publicationDate |
2004-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6750025-B1 |
titleOfInvention |
Method of detecting and isolating prion protein and variants thereof |
abstract |
The present invention provides for a novel method of detecting the prion protein and variants thereof which utilizes specific amino acid binding sequences. Specifically, the present invention provides a method of detecting prion proteins, as well as isolating prion proteins, using an agent that binds to the amino acid sequence Gln-Pro-His of prion proteins. Further provided by the present invention is a method of diagnosing prion diseases in a subject using an agent that binds to the amino acid sequence Gln-Pro-His of prion proteins. Also provided are methods of treating and preventing prion diseases in a subject by administering an agent that binds to the amino acid sequence Gln-Pro-His of prion proteins. Finally, a method of inhibiting the dissemination of prion diseases through ingestion or exposure to liquid or solid substances by treating of the liquid or solid substance with biotin is provided herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026070-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7393658-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7691639-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005014196-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8673579-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7166471-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003104633-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7863411-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011009604-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008171341-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006024736-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010009388-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006057671-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006088281-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005282238-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005214805-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9638702-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011081660-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008095706-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7510848-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006078892-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006199194-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286672-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006275910-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8062895-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008268474-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9678085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004229280-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8604161-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8372593-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005026165-A1 |
priorityDate |
1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |