abstract |
Compounds according to the formula A-Z-W as herein described, wherein A is selected from the groups consisting of: A'-(CH2)n-, A'-(CH2)nSO2-, and A'-(CH2)nCO-, where n is 0 to 4; and A' is selected from(a) (C6-C10)aryl-, or(b) (C1-C9)heteroaryl-; which groups may be optionally substituted; and pharmaceutically acceptable salts, solvates or hydrates thereof; pharmaceutical compositions thereof; and methods useful to facilitate secretion of growth hormone(GH) in mammals. |