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publicationDate 2004-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6716973-B2
titleOfInvention Use of a ribozyme to join nucleic acids and peptides
abstract Engineered mRNA useful in producing libraries of engineered mRNAs, polypeptide-engineered mRNA conjugates and diverse encoded polypeptide libraries, as well as novel ribozymes that join an mRNA to the translation product of the mRNA and methods of identifying members of diverse encoded polypeptide libraries which exhibit a desired activity. Also described are polypeptide-nucleic acid tag conjugates, methods of producing the conjugates and uses therefor.
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