| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53fa142d8ca59b115fc3f2bdf8c3f7a2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-645 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate |
2003-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80cc5fcdb71b14e6780ec455a55e4d05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf4bacd94d224a6e0238efa6f0c1a8f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f721f22d9383cecbdeeb373499f08477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9baa7a02a375af7a3fad57dae0240da8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_375d99d3ecd285c71ad4a49db8a3bebd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fba9a41fa8d1323c1f0276d3cdc80a3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55956ff7f4e3d3d26910775248281f76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b3dbe267fb8bb6be3904b3ba4d7456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f6ba84e407b5a9a5d9c1d9028df9011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3529aa97517caeeeadffd0c2cf5a971e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7acef8c4b11339cf7350e2d9c593ca68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a75540546fe646bb29c34ae5c819435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83fd74729044ad7a64f13838637798e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c2b6a904e676abecd2785d8034a7ddb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ed4af5b2b4e4f2920ddeb9cdbfe9511 |
| publicationDate |
2004-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6696599-B2 |
| titleOfInvention |
Microbial process for preparing pravastatin |
| abstract |
The present invention relates to a new microbial process for the preparation of the compound formula (I)from a compound of general formula (II)wherein R stands for an alkali metal or ammonium ion, by the submerged cultivation of a mold strain able to 6beta-hydroxylate a compound of the Formula (II) in aerobic fermentation and by the separation and purification of the product of Formula (I) formed in the course of the bioconversion. The process comprises cultivating a strain of Mortierella maculata filamentous mold species that is able to 6beta-hydroxylate a compound of the general Formula (II), on a nutrient medium containing assimilable carbon and nitrogen sources and mineral salts and separating the product formed from the fermentation broth, then isolating the compound of formula (I) and purifying the same. Novel strains of Mortierella maculata are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7795458-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7425644-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163942-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007197633-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004115781-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008300305-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006252826-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011003993-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001041809-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006194984-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7001919-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005288370-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7262218-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7585988-B2 |
| priorityDate |
1999-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |