| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de094784025e53546f898a3de5a5e393 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-20 |
| filingDate |
2001-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a65f22817fd4a53992b64043c6ee4242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3dff17f1cf63231ddb0aacb654df366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8111c2528dcc5b5d083e30ec087a9288
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582a9a4438574b38098094dca364a9ce |
| publicationDate |
2004-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6689364-B2 |
| titleOfInvention |
Borrelia burgdorferi polypeptides and uses thereof |
| abstract |
The present invention provides novel polypeptides which are substantially free of a B. burgdorferi spirochete or fragments thereof and which are thus useful in compositions and methods for the treatment and prevention of B. burgdorferi infection and Lyme disease. In one preferred embodiment, this invention provides modified OspA polypeptides and pharmaceutically effective compositions and methods comprising those polypeptides. Preferred modified OspA polypeptides are characterized by modifications which diminish and/or ablate their ability to bind the human MHC allele HLA-DRB1*0401. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023367-B2 |
| priorityDate |
2000-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |