Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7151 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2004-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6f7a377f4d390dc10d60fc3c361b775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b6e03eda5131fe2d4086fd0806ae1e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4138f37a0ed372f2d9e984bc62ea4d43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cebf65443baa4c8b222911d41b9ca935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c38a886d7edbe6e0b0c6b075b67a8601 |
publicationDate |
2004-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6682739-B1 |
titleOfInvention |
Methods of inhibiting osteoclastogenesis |
abstract |
Methods of inhibiting osteoclastogenesis and the activity of osteoclasts are disclosed. Methods of treating patients who have diseases characterized bone loss are disclosed. The present invention also provides peptides and peptide analogues designed from a binding loop of a member of the tumor necrosis factor receptor (TNF-R) superfamily. According to the methods, an amount of an inhibitor effective to inhibit osteoclastogenesis is administered to the patient. Methods of modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems in an individual are disclosed. The methods comprise the step of administering to the individual an amount of an inhibitor effective to modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010260680-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010083084-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9376467-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9365615-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004170621-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004138162-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10633418-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10654891-B2 |
priorityDate |
1999-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |