http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6663892-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1be70312cf7ed65482cc6fe85d329525 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 |
filingDate | 2002-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e345af8a356e44b01b3de7d56397332 |
publicationDate | 2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6663892-B1 |
titleOfInvention | Multiple portion tablet |
abstract | A solid orally administrable pharmaceutical dosage form for the treatment of gastric disorders includes a first portion containing a therapeutically effective amount of a histamine H2-receptor antagonist, and a second portion immediately adjacent the first portion without an intervening barrier disposed between the first portion and the second portion, the second portion containing a therapeutically effective amount of an antacid. Physical separation of the active ingredients into two different portions without a separating barrier has been found sufficient to prevent degradation of the histamine H2-receptor antagonist due to contact with the antacid. The invention therefore provides stabilization of a histamine H2-receptor antagonist-antacid combination tablet which is comparable to known multiple portion tablets, but without an intervening barrier between the antacid portion and the histamine H2-receptor antagonist portion. Therefore, the benefits of the prior art are achieved at a reduced cost by eliminating a barrier and manufacturing steps associated with the provision of a barrier, as is conventional. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005192920-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012282570-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8765178-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008020039-A1 |
priorityDate | 2002-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.