http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6660853-B2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 |
| filingDate | 2001-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98e3297e5117113d0260373a320a5d95 |
| publicationDate | 2003-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6660853-B2 |
| titleOfInvention | Method for purifying high molecular weight hyaluronic acid |
| abstract | A method for purifying high molecular weight hyaluronic acid, comprising the steps of providing one or more raw hyaluronic acid sources; extracting hyaluronic acid from the source; precipitating hyaluronic acid extracts; dissolving extract precipitates in water; extracting enzyme inhibitors from the dissolved precipitates with chloroform, and centrifuging to isolate an aqueous portion; adding one or more protein hydrolyzing enzymes to the aqueous portion in a reactor; adding a solution of CPC and NaCl to the reactor; filtering reactor contents through at least one membrane filter; filtering membrane filtered solution through at least one diafilter having a molecular weight cutoff of about 30 kDa; precipitating the diafiltered solution and isolating purified hyaluronic acid precipitate; and formulating isolated precipitate to about 10 mg/ml hyaluronic acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315588-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005118607-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124752-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101633701-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005267301-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7002007-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3896152-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013142254-A1 |
| priorityDate | 2000-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.