Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be944a7839fc8cabe752928d03dafaa4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-20 |
filingDate |
1998-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a786ad0cf4a792e13b21bccfb3a9d902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_593260cc241f454a656054e76c6ecbb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e527782aed4ceaf74adadc5721a66071 |
publicationDate |
2003-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6656734-B1 |
titleOfInvention |
Compositions for the delivery of polynucleotides to cells |
abstract |
The present invention relates to a composition which is intended for transferring at least one therapeutically active substance into the interior of a target cell, characterized in that it comprises a mixture of at least one therapeutically active substance and at least one polar compound which is selected from a specific group of aprotic polar compounds. The therapeutically active substance is preferably a polynucleotide, and the polar compound is DPSO, which improves the ability of the polynucleotide to be transfected into the interior of the cells. The compositions according to the invention can be used as a diagnostic therapeutic, prophylactic or vaccinal medicament for treating the human or animal body by means of gene therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652526-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7851212-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011229975-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8003621-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9572886-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11118226-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11118214-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013040294-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004223949-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8686052-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8574623-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662465-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022064716-A1 |
priorityDate |
1997-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |