| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3922fce49131c3acfa7e3def53ae15cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 |
| filingDate |
2000-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54aeb5dbae0be1ffb9176c727e12c186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cf16411593d1898939d1cb54dd934e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51d681cd2769a71a065d0239365155b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b2dafa901efd7f735d3eaf0d4703a01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c42e8e05c8406595633e18c9d13aa66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfa94191c9d39b4d836ad5de692b9d3e |
| publicationDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6630303-B1 |
| titleOfInvention |
Methods of screening for compounds active on Staphylococcus aureus target genes |
| abstract |
This disclosure describes isolated or purified deoxyribonucleotide (DNA) sequences, useful for the development of antibacterial agents, which contain the coding sequences of bacterial pathogenesis genes or essential genes, which are expressed in vivo. It further describes isolated or purified DNA sequences which are portions of such bacterial genes, which are useful as probes to identify the presence of the corresponding gene or the presence of a bacteria containing that gene. Also described are hypersensitive mutant cells containing a mutant gene corresponding to any of the identified sequences and methods of screening for antibacterial agents using such hypersensitive cells. In addition it describes methods of treating bacterial infections by administering an antibacterial agent active against one of the identified targets, as well as pharmaceutical compositions effective in such treatments. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103314573-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9369643-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103314573-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188722-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011048195-A1 |
| priorityDate |
1995-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |