http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6627744-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2de1389433aab193063aa0a2c8c693d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6898 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-10 |
| filingDate | 2001-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c692310a54a9137dffe1879cc93604e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af69d6786ed3b26c80cdc909e8ec7f11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86e19133c6f8100babfd8ab1eb4ed87 |
| publicationDate | 2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6627744-B2 |
| titleOfInvention | Synthesis of glycodendrimer reagents |
| abstract | The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine residue with a glycosylated thiosulfonate. Also a method of producing the chemically modified mutant protein is provided. The present invention also relates to a glycosylated methanethiosulfonate. Another aspect of the present invention is a method of modifying the functional characteristics of a protein including providing a protein and reacting the protein with a glycosylated methanethiosulfonate reagent under conditions effective to produce a glycoprotein with altered functional characteristics as compared to the protein. In addition, the present invention relates to methods of determining the structure-function relationships of chemically modified mutant proteins. The present invention also relates to synthetic methods for producing thio-glycoses, the thio-glycoses so produced, and to methods for producing glycodendrimer reagents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9283247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658148-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008317699-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004180852-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9611357-B2 |
| priorityDate | 1999-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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