| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6478
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8fb5e79afb58766b8d510c76c4d5bee |
| publicationDate |
2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6627409-B2 |
| titleOfInvention |
Assay for Alzheimer's disease drug development |
| abstract |
This invention provides a method of determining the proteolytic activity of the in vivo secretases, particularly the β-secretease and γ-secretease that produce the Aβ peptides found in the plaques of Alzheimer Dementia (AD) patients. The invention also provides methods of isolating such secretases and methods of selecting agents that affect the activity of such secretases for developing drugs to treat or prevent dementia. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006223849-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8637274-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011065713-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009326006-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010093010-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8598353-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005112696-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7893267-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007292895-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010035927-A1 |
| priorityDate |
1998-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |