| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c66f9e0be61e4f51b54b0bc2eb0bd167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d030ba99c0ca7985cfd3566b67c50a2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1998-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a04c26faa30e900ca50cc8e0462e76d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dfb48b70e788f03ef8a45ceb419d969 |
| publicationDate |
2003-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6620914-B1 |
| titleOfInvention |
Transcription factor islet-brain 1 (IB1) |
| abstract |
The identification and characterisation of human and rat Islet-Brain 1 (IB1) is disclosed, a transcriptional activator that is involved in the control of the GLUT2 and insulin genes by interacting with homologous cis-regulatory elements of the GLUT2 and insulin promoters. The rat IB1 cDNA encodes a 714 amino acid protein and the human IB1 cDNA a 711 amino acid protein. The use of IB1 polypeptides, nucleic acid, agonists and antagonists in the treatment or diagnosis of diabetes, neurological diseases such as dementia and/or parkinsonism, the inhibition/promotion of apoptosis and cancer is disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624948-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002012932-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11331364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6759197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10967038-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596223-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779628-B2 |
| priorityDate |
1997-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |