http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6620616-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e72837de81999e7e72cb78d59d19e28 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-13039 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
filingDate | 2000-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c85d57f8603f8ae6bc201721bd18e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a349ee99a16c6a6c570b0b85dd36d76 |
publicationDate | 2003-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6620616-B1 |
titleOfInvention | Nucleic acids encoding nitric oxide synthase variants |
abstract | Isolated polynucleotides which encode a variant of a mammalian nitric oxide synthase protein or polypeptide are provided. The variant nitric oxide synthase protein and polypeptides are substitution mutants, wherein the tryptophan that is normally located on the alpha 3 helix, six residues upstream from the cysteine which binds heme in the corresponding non-variant nitric oxide synthase protein or peptide is replaced with one of the other 19 naturally-occurring amino acid residues. The present invention also relates to vectors and recombinant cells comprising a nucleic acid which encodes a variant of a mammalian nitric oxide synthase protein. The present invention also relates to the nitric oxide synthase variant proteins and polypeptides. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004096881-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004016764-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004045709-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004016764-A2 |
priorityDate | 2000-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.