| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ef0abbcc9f8c4252a19802021dca2a7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-00 |
| filingDate |
2001-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8544bc81283cbfb9d771e1a5f9e162a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba8f1fbe8422eb60056b39bf0ca4e41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3ef599c39fef40dbd15f33533f4cd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e174bb6487cb193d4daef26032c9f3d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45a74347164bc344c7d832f3403db17 |
| publicationDate |
2003-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6613804-B2 |
| titleOfInvention |
Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
| abstract |
Biphenylsulfonamides and methods for modulating or altering the activity of the endothelin family of peptides are provided. In particular, bicyclic or tricyclic carbon or heterocyclic ring biphenylsulfonamides and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods for treating endothelin-mediated disorders by administering effective amounts of one or more of these sulfonamides or prodrugs thereof that inhibit or increase the activity of endothelin are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7524880-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009018084-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463656-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005277688-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108130188-A |
| priorityDate |
1993-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |