| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7fe151308388476e056181c18272ea4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-929 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B8-00 |
| filingDate |
1999-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fab7c32fde653c6a5aa8698f0013629
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc392a1813a5d6e2762421e6e476fb4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e8370f8c5eaeb02f6ca810048d7e03e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51b282ab01fed8c344e89335838f5b14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79c884e2e1cc3bec656dd372f9587de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dd0d4ea25e02adc41984c5d1cf6026f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e19b0cd2f8bba749e879e0e5f536dc3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bac89b96a98bcefec3e86bab8660b67 |
| publicationDate |
2003-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6613306-B1 |
| titleOfInvention |
Ultrasound contrast agents and methods of making and using them |
| abstract |
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain surfactants and, optionally, hydrophilic stabilizers. The surfactants can be in the form of liposomes. The suspensions are obtained by exposing the surfactants to air or a gas before or after admixing with an aqueous phase. One can impart outstanding resistance against collapse under pressure to these gas-filled microbubbles used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditions, divided by the square root of the molecular weight does not exceed 0.003. Contrast agents with particular mixtures of gases are also disclosed that have advantageous properties. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010076320-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9427396-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007009431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012136813-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008138290-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11266751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11266752-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011172486-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006222694-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006257321-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008260790-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586005-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9910020-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008139973-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10980898-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8012457-B2 |
| priorityDate |
1990-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |