| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95f9c4f40276e5e0e07f3654f3b4cfde |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57563 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 |
| filingDate |
2000-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b52e3d6505bec98cbd0fc99cdc05ace
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0faf3810756c02d20a5eebbf996e8150
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a18a9e242837888cc04e1e6bf0455e27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_900c5ee283bae63f8283453f9c68b712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b8387cef2e1e1d918b78e1cdad88cf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0bf61ded37f37a5eb91ca910be56132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5923930ef1c4b7a4b1a4703ff6013989
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90df3703f03a4037cf2a6339b9aef9cb |
| publicationDate |
2003-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6608174-B1 |
| titleOfInvention |
Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy |
| abstract |
The present invention encompasses radiolabeled peptide analogs of vasoactive intestinal peptide (VIP) labeled with a radionuclide useful for imaging target sites within mammalian living systems. The invention particularly provides radiolabeled VIP derivatives that bind selectively to the VIP receptor on target cells. Specifically, the invention relates to the radiolabeling of VIP-receptor specific agents and their subsequent use for radiodiagnostic and radiotherapeutic purposes. The invention encompasses methods for radiolabeling these peptides with radio-nuclides and the use of these peptides as scintigraphic imaging agents. The radiolabeled VIP derivatives of the present invention exhibit pharmacological activity and therefore are useful as either imaging agent for visualization of VIP-receptor positive tumors and metastases, as a radiodiagnostic agent or as a radio-therapeutic agent for the treatment of such tumors in vivo by specifically targeting the cytotoxic radionuclide selectively to the tumor site in mammalian living systems. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9782454-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10543255-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012170524-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278595-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014126904-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011133948-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180021253-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9789164-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3311828-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016130518-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10772934-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011133948-A2 |
| priorityDate |
2000-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |