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filingDate 1997-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2003-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6605594-B2
titleOfInvention Aqueous glycerol formulations of somatotropin
abstract Aqueous somatotropin compositions are presented that contain less than about 10% of a biologically active somatotropin, water, and glycerol in an amount effective and at a pH effective to maintain the somatotropin substantially completely stable. The somatotropins in such compositions preferably retain their physical and chemical stability for at least 2 years. The somatotropin compositions also preferably have anti-microbial activity, such that, after they have been sterile-filtered, no additional anti-microbial agent is necessary to maintain the sterility of the composition.
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