| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99505f5f312672820e9f78c254c00a4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f352cc5bd193c17ffff15bf60e16f7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
1999-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_015f751bfb0acc20161d0a32e0cefddf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_134af9c2a0b790eef3f941f1c7e7dcd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_101a8cd7003fa35be1512e7bdfae687a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b020fabb208efc0e629130303fee2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eefe93ee4d8a6cdd918bc4de01a24a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b7e3a4ab92dd3e43721725ec1a8da04 |
| publicationDate |
2003-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6605436-B1 |
| titleOfInvention |
Method and kit for detecting intrachromosome imbalance in interphase nuclei and their applications |
| abstract |
The invention concerns a method for detecting intrachromosome imbalance in interphase nuclei, characterized in that it consists in: (a) hybridizing in situ the chromosome suspected to be affected by said imbalance using two probes marked with different fluorochromes and specific of said chromosome long arm and short arm respectively; (b) measuring the intensity of the fluorescence emitted in said nuclei with different emission wavelengths corresponding to each of the two fluorochromes; (c) calculating the ratio (Ra) between the two measured values of fluorescence intensity; and (d) comparing the resulting ratio value with at least one reference value. The invention also concerns a kit for implementing said method and uses of said kit and said method, in particular for detecting cancer cells in a biological sample and for diagnosing cancer pathologies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005042609-A1 |
| priorityDate |
1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |