| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_611b00a4d5f7b339163e4d97a7c48936 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
1998-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51efc8f44bfb5af68bc5cad9f060e10d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a4347da38a7dacd1bdf0a2c10ab0747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93a8b166e63f3055c823beeab947dcd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c6769371f8959083345449ac241fb7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_facea03f0468b224031421a7aea616c6 |
| publicationDate |
2003-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6593084-B2 |
| titleOfInvention |
Carcinogen assay |
| abstract |
The present invention is drawn to methods and assays for the early determination of whether a test agent is a carcinogen. These novel methods and assays are used to correlate the pattern of differential gene expression from mammalian cells treated with the test agent with reference patterns of differential gene expression of mammalian cells treated with known carcinogens. Further, the present invention is drawn to methods of use of DNA and RNA isolated from the treated mammalian cells as well as kits comprising same. The present invention also is drawn to methods of determining whether a test agent is a carcinogen by measuring protein synthesis or post-translational modifications from mammalian cells treated with the test agent compared with mammalian cells treated with a known carcinogen. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004049249-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003236394-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005055072-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009233211-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009093867-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7524327-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004264853-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7704272-B2 |
| priorityDate |
1998-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |