abstract |
Disclosed are novel compounds represented by Structural Formula II, IX or XXVIII:R1, R2, and R22 are independently an aliphatic group, a substituted aliphatic group, an aromatic group or a substituted aromatic group.R2 is -NR4R5 or -N+=C-.Alternatively, R1, and R2, taken together with the methine group to which they are bonded, are a moiety represented by the following structural formula:R3 is -NH2, -OH, -OC(O)H or -OR9.R5, R6 and R7 are independently -H or an amine protecting group.R8 is -H, -OH or -OR8.R9 is an alcohol protecting group.Also disclosed are methods of preparing these compounds. |