| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ae609b1f14b3fb56a927f7b5c15b67 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-1827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-1822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0877
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0684
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L9-527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00659
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-1866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0481
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-50853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate |
1999-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7082058c4779c013d8920a28c78f915a |
| publicationDate |
2003-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6589778-B1 |
| titleOfInvention |
Method and apparatus for performing biological reactions on a substrate surface |
| abstract |
The present invention provides an apparatus for performing biological reactions on a substrate layer having a multiplicity of oligonucleotide binding sites disposed thereon. The invention provides a hybridization chamber wherein nucleic acid hybridization is performed by reacting biological material on a biochip comprising a substrate having an array of oligonucleotide binding sites. The binding sites are associated with an array of 3-dimensional polyacrylamide pads for anchoring the reactants. The arrays are covered with a flexible layer that permits mixing of the hybridization solution on the biochip and detection of hybridization in situ. Fluid inlet and outlet ports in the chamber provide for control of fluid flow into and out of the chamber. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9557115-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-2019044-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7166258-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003134410-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003068253-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003064507-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7687437-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007009914-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7224474-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003152957-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617087-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003157503-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005170401-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7494776-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012111535-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006176492-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004018523-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113070113-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113070113-B |
| priorityDate |
1999-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |