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filingDate 2001-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4f10ea802fc7dfe7b030c294cf49e2e
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publicationDate 2003-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6576218-B1
titleOfInvention Transplacental delivery of oligonucleotides
abstract This invention provides synthetic oligonucleotides that are useful for transplacental delivery, the oligonucleotides being DNA or RNA or both, preferably between 12-35 nucleotides in length, having a stabilized and charged backbone and at least one chemically modified base or sugar moiety, wherein the modified base or sugar moiety facilitates transplacental delivery.
priorityDate 1997-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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