Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5819d0705b09a0114e9e1681851442a8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0023 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate |
2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcf97786d8ecd8f7e8cd75cf79313e23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c68877e7c86157dee31d4b4ef35fa64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5eba0f7c41e1ece3aa82950f56c6e6c |
publicationDate |
2003-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6566504-B2 |
titleOfInvention |
Process for viral inactivation of lyophilized blood proteins |
abstract |
A process for inactivating viral contaminants of lyophilized Factor VIII by heat is provided. The process comprises forming a stable complex between the Factor VIII and a cyclodextrin in an aqueous solution. The solution is then lyophilized, and the Factor VIII/cyclodextrin complex is recovered. The lyophilized Factor VIII/cyclodextrin is then heated to 60° C. to inactivate any virus present. The material may then be reconstituted prior to administration to a patient. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7989593-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11740019-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11747082-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048856-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8106011-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634257-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610528-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609042-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609043-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7932356-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8084581-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011136815-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11604026-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8735374-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9717682-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011028431-A1 |
priorityDate |
1996-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |