http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6559161-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d12b35c0dd9adfb167b3b4f383afe93 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-06 |
| filingDate | 2000-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49cead54f5da6b7c889acc4500c08bf8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f931ed976eab98747d76d5f015d90c36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c018f39a92bdbe37fb2d52e5df429685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f638c0e542dddc0b5d395b9b9ed255a |
| publicationDate | 2003-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6559161-B1 |
| titleOfInvention | Cytotoxic pyrido[2,3,4-ki]acridine derivatives, their preparation and their therapeutic use |
| abstract | The invention provides compounds of formula (I)whereinR1 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a hydroxy group, an alkoxy group having from 1 to 6 carbon atoms, a halogen atom, a nitro group, an amino group, a monoalkylamino group wherein the alkyl moiety has from 1 to 6 carbon atoms, a dialkylamino group wherein each alkyl moiety may be the same or different and each has from 1 to 6 carbon atoms, a dialkoxyamino group wherein each alkoxy moiety may be the same or different and each has from 1 to 6 carbon atoms, an alkanoyalmino group having from 1 to 20 carbon atoms or an alkanesulfonylamino group having from 1 to 6 carbon atoms;R2 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms; andR3 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms or an alkoxy group having from 1 to 6 carbon atoms;and pharmaceutically acceptable salts thereof. The compounds exhibit activity against a wide variety of mammalian cancer cell lines. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007039600-A1 |
| priorityDate | 1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 469.