http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6558678-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-849 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 |
filingDate | 1992-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b18131ce30b81a9c80abb82f1fae0797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52283391c7c538e2643241e20e3e2f4b |
publicationDate | 2003-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6558678-B1 |
titleOfInvention | Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e. coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e. coli bacteria in humans |
abstract | Disclosed is a method of producing a vaccine composition against enteric infection caused by enterotoxigenic E. coli bacteria in humans. E. coli strains selected from different known strains each having the ability of expressing a certain type of colonization factor antigens are grown in a liquid culture medium. Finally formalin-killed E. coli strain having substantially preserved antigenic and hemagglutinating properties of said certain type of colonization factor antigens, is mixed with a pharmaceutically acceptable excipient and/or diluent. Further disclosed is a method of preventing an enteric infection caused by enterotoxigenic E. coli bacteria in humans, whereby a vaccine composition comprising inactivated E. coli strain is administered to a human being for the prevention of said infection. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005025787-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012082648-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019039948-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014065186-A1 |
priorityDate | 1991-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.