Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3873abaff397acbfffa1595a12cfef41 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2000-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac24c9709ee517dcbff9d5635f4f9347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_541162ec02cdb08156e2c9adb630259b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_952abcb31280fb20785a13f7c18fed8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65efa8b09639adb93bd7b1ffe7e05176 |
publicationDate |
2003-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6551781-B1 |
titleOfInvention |
Methods of screening for compounds that regulate the level of Nramp |
abstract |
The present invention relates to mouse and human cDNAs for a gene family designated Nramp (natural resistance-associated macrophage protein), involved in macrophage function and responsible for the natural resistance to infection with intracellular parasites, and to the isolation of Nramp sequences from other animal sources. The nucleotide sequences of the mouse and human cDNAs are disclosed, as are the amino sequences of the encoded products. The cDNAs can be expressed in expression constructs. These expression constructs and the proteins produced therefrom can be used for a variety of purposes including diagnostic and therapeutic methods. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012068229-A1 |
priorityDate |
1993-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |