http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6548509-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40a92325286ca98dbffa06d2c67ed064 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93665e3fc9cc00f9d7bc090b3eae1931 |
| publicationDate | 2003-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6548509-B2 |
| titleOfInvention | 3-aryl substituted pyrazolo[4,3-D]pyrimidine derivatives; corticotropin-releasing factor receptor (CRF1) specific ligands |
| abstract | This invention encompasses compounds of the formulawhereinAr represents a mono-, di- or trisubstituted aryl group where at least one position on Ar ortho to the point of attachment to the pyrazole ring is substituted; andR1 represents lower alkyl;R2 is hydrogen or lower alkyl; andR3 and R4 independently represent organic and inorganic substituents,which compounds are highly selective partial agonists or antagonists at human CRF1 receptors and are useful in the diagnosis and treatment of treating stress related disorders such as post traumatic stress disorder (PTSD) as well as depression, headache and anxiety. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6962915-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2527446-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2527447-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2270034-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004023992-A1 |
| priorityDate | 1999-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 298.