| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c123a954414370f8e9cd69e568fe92f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate |
2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f620909e8873874753c5a671c87513b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_968ef6512b88374fb76c4e3b62f4e540
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d7efec6b450688918b189faec56a30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d932138190019755570af37deacc890
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d05aec9cae4d2896fb43cd54442d3a8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad48dadd045263a602c107ba8e18bfe3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c76c70d8fc16dd213f346ee7dac4bb0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cee799d84d94cca1208647fbba2ec21 |
| publicationDate |
2003-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6548265-B2 |
| titleOfInvention |
Treatment or prophylaxis of diseases caused by pilus-forming bacteria |
| abstract |
Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10221411-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005265922-A1 |
| priorityDate |
1993-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |