| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04481c68d907208b086a245a70cf0708 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-30 |
| filingDate |
2000-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a83ab3b6d0ac56b6601c6f38e034be85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_639e4b587692fc68598e49a2c67c99b8 |
| publicationDate |
2003-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6545152-B1 |
| titleOfInvention |
R-isomers of nonnucleoside inhibitors |
| abstract |
Novel chiral derivitaves of non-nucleoside inhibitors (NNI), particularly R-isomers of halopyridyl and thiazoyl thiourea compounds are provided as potent inhibitors of reverse transcriptase (RT), and particularly of retroviral RT, most particularly HIV RT. The stereospecific compounds and compositions of the invention inhibit replication of retrovirus, particularly human immunodeficiency virus-1 (HIV-1) and drug resistant strains. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103003236-A |
| priorityDate |
2000-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |