http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6537996-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1db1ad56a68b4ccd66dc83c1eed6a9b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2001-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b10cf31d746a9e70e10f44b6edd255b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d38dfad4766799f72eb96d089b538e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_877eb5d8ad98ecae1ee56100c45f4cb3 |
| publicationDate | 2003-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6537996-B2 |
| titleOfInvention | Modulators of p38 MAP kinase |
| abstract | Compounds of formula 1 are effective modulators of p38 MAP kinase.wherein R1 is H, lower alkyl, or OR5, where R5 is aryl, heterocyclyl, acyl, N-R6-4-piperidinyl, N-R6-4-piperidinylmethyl, or N-R6-4-pipelidinylethyl, where aryl and heterocyclyl are substituted with 1-3 R6 substituents selected from the group consisting of H, lower alkyl, lower alkenyl, OH, NO2, NH2, halo, trihalomethyl, -CN, SH, SO, SO2, SO3H, -OR, -COR, -COOR, -CONHR, -OCOR, and -NCOR, where R is lower alkyl; R2 is H or lower alkyl; R3 is aryl substituted with 1-3 R6 substituents; R4 is H, lower alkyl, aryl, aralkyl, -OH, -NH2, -NHR, or -OR, where R is lower alkyl or aryl-lower alkyl; and A is -CH- or -N-; and pharmaceutically acceptable salts thereof. |
| priorityDate | 2000-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.