http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6531296-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate | 1995-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_859e18cd8408af53631168171fbef292 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1581d5e096158150e45fcb04a75abd35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fc283a7faba6c3895ac62d9ffa0aaa0 |
publicationDate | 2003-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6531296-B1 |
titleOfInvention | Nuclear tyrosine kinase Rak |
abstract | A nuclear tyrosine kinase called Rak has been identified. This tyrosine kinase is expressed primarily in epithelial cells, and has been found to be a growth inhibiting kinase. Domains of the Rak protein, and corresponding peptides, have been found to inhibit CDC2 function and therefore block the cell cycle and inhibit cell growth. A domain of the Rak protein which binds to the retinoblastoma gene product has also been identified, and is in a domain distinct from the CDC2 binding region. Peptides which bind to CDC2, and peptides which bind to the retinoblastoma gene product, are described. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007213257-A1 |
priorityDate | 1995-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 924.