| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1997-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f08c65ecf3e01d4381771fc7a9645cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38779f94d406b1fd746412f276c91f55 |
| publicationDate |
2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6528479-B1 |
| titleOfInvention |
Dominant negative mutants of IRS-1 and uses thereof |
| abstract |
Dominant negative mutants of mammalian IRS-1 proteins and therapeutic compositions containing such mutants. Also featured are methods of using the dominant negative mutants to inhibit tyrosyl phosphorylation of endogenous IRS-1 in mammalian cells and methods of treating a mammalian malignancy in which tyrosyl phosphorylation of endogenous IRS-1 plays a causative role. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7884078-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007299010-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008125388-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010113577-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008227745-A1 |
| priorityDate |
1996-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |