| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_857f8336175d4a3144facf2e9ad3998b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
1999-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45da784f2881a59e1247991e528ddb32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bb72689072c5ca798346bc3f1119aa2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ecdcfbf9094d031564508d8008e9fe6 |
| publicationDate |
2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6528261-B1 |
| titleOfInvention |
Method for typing of HLA alleles |
| abstract |
The present invention relates to the typing of HLA alleles. The sequence of exon 2 and exon 3 of the alleles HLA-B*3913, HLA-B*1406 and HLA-B*51new and of exon 2 of the alleles HLA-DRB1*0820, HLA-DRB1*04new and HLA-DRB4*01new are disclosed. The present invention also relates to methods of typing of such alleles. According to a particular embodiment, typing of alleles is achieved by: i) amplifying a relevant fragment of the alleles with at least one suitable set of primers; ii) hybridizing the amplification product of step i) to at least one probe that specifically hybridizes to a target region comprising one or more polymorphic nucleotides in said relevant fragment; and iii) determining from the result of step ii) the absence or presence of the alleles in the sample. The present invention further provides primers and probes to be used in such methods of typing alleles. Diagnostic kits comprising such primers and probes are also included within the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010086914-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010261189-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006039673-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005042764-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012157347-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009208947-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007065860-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007076001-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435740-B2 |
| priorityDate |
1998-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |