| abstract |
An optical system and method for transcranial in vivo examination of brain tissue includes a spectrophotometer coupled to an array of optical fibers and a processor. The array of optical fibers is constructed to transmit optical radiation of a visible to infra-red wavelength. The optical fibers have distal ends projected through the hair into contact with a surface of the scalp and arranged over a selected geometrical pattern. The spectrophotometer includes at least one light source constructed to emit optical radiation of the visible or infra-red wavelength and at least one light detector constructed to detect radiation that has migrated from a first of said distal ends within the brain tissue to a second of the distal ends. A sequencer is constructed to control introduction of radiation from a first distal end and constructed to control detection of radiation after arriving at a second distal end using a transmission/reception algorithm over the geometrical pattern. A processor is arranged to provide the transmission/reception algorithm and receive signals of the detected radiation from the detector, wherein the processor is arranged to produce a succession of optical data sets over time to monitor evolution of a tissue state of the examined brain tissue. |