| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9259cfa966fe620251340a003f5d6125 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2000-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f5de013625c6d0854e48ecaf19e850a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aec82285553ea7af2944ff63607bb50 |
| publicationDate |
2003-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6518011-B1 |
| titleOfInvention |
Method for screening compounds to identify beta-amyloid production modulators |
| abstract |
The present invention is directed generally to methods and composition for monitoring the processing of epitope-tagged beta-APP. More specifically, the present invention relates to the use of such methods and composition for monitoring responses of cells expressing such epitope-tagged beta-APP or fragments thereof or cell free systems containing the epitope-tagged polypeptides to therapy of diseases associated with an altered metabolism of the beta amyloid precursor protein (APP), and for screening and evaluation of potential drugs for the treatment of these disorders, including Alzheimer's disease (AD). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03072037-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003199003-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03072037-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010081147-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007190046-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927225-B2 |
| priorityDate |
1999-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |