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filingDate 2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f019cc51d826568d77647d5407a4c0b
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publicationDate 2003-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6509037-B2
titleOfInvention Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
abstract The present invention provides a novel sustained release composition and method for making such a composition of diclofenac and its pharmaceutically acceptable salts. The composition of the present invention provides a sustained release formulation of diclofenac and pharmaceutically acceptable salts thereof which is suitable for once daily administration and provides controlled and long lasting in vivo release. The composition comprises: (a) about 5-25% by weight of hydroxyethyl cellulose; (b) about 5-75% by weight of lactose; (c) about 0-3% by weight of silicone dioxide; (d) about 0.5-5% by weight of PVP; (e) about <3% by weight of talc; and f) about <3% by weight of magnesium stearate.
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