http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6503727-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2427716fc69ab2e2d3493d8d6385c6aa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate | 1996-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e61ed5a963309f7e0174828c76521689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_174635016bf20b5f418ab48042a2867f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4e90633336a994e0db4ce911a7814d8 |
| publicationDate | 2003-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6503727-B1 |
| titleOfInvention | Process for the preparation of an antibiotic |
| abstract | The invention relates to a process for the preparation of an antibiotic, in particular cefalexin, ampicillin, amoxicillin, cefaclor, cefradin, cefadroxil, cefotaxim and the like, wherein a beta-lactam core is acylated, the antibiotic is recovered from the reaction mixture, the remaining mother liquor is subjected to a hydrolysis reaction in which the antibiotic present in the mother liquor is decomposed into its initial compounds, in particular the beta-lactam core, and the acylation agent is hydrolized. The beta-lactam core can then be recovered virtually quantitatively or recycled to the acylation reaction. This is because it has been found that the solubility of the beta-lactam core is unexpectedly high at relatively high concentrations of acylation agent and antibiotic. |
| priorityDate | 1995-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.