Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83ebcb287b2343acc6752fb97ce7e806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f244c6155c2c1d73694b62b1c889927 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
1998-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79fda0afdee8cac15dadb9e450a87db5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be523f3eb4ea7e5cbce83dac76729222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15788710bf5f8e1fc841d06ccdf22cc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75028001fc23bb59e68d82637d5e1fc6 |
publicationDate |
2002-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6489454-B1 |
titleOfInvention |
Engulfment gene and uses thereof |
abstract |
The invention relates to a signal transduction pathway which promotes phagocytosis of apoptotic cells and in particular relates to a protein known as CED-6 in the nematode worm C. elegans, human equivalents of CED-6 protein and nucleic acids encoding them. The invention also relates to use of the proteins and encoding nucleic acids in assay methods for detecting compounds which enhance or inhibit the signal transduction pathway and use of the proteins, nucleic acids and identified enhancer or inhibitor compounds in methods of treatment of human or animal disease. |
priorityDate |
1998-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |