| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate |
1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37bcd2e6bf1c6ef6493e4e73c4f65f1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3c220d1d92c6085e7f6f4b72f3dfb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45d8c593997733a009e5d62b273deb76 |
| publicationDate |
2002-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6489322-B1 |
| titleOfInvention |
Amidine derivatives as inhibitors of nitric oxide synthase |
| abstract |
There are provided novel compounds of formula (I)wherein R1 represents a 2-thienyl or 3-thienyl ring and R2 represents hydrogen or C 1 to 4 alkyl and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are selective inhibitors of the neuronal isoform of nitric oxide synthase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183712-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008144483-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263587-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007082897-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011152247-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7713963-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009166652-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008144483-A2 |
| priorityDate |
1997-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |